|
（単位：千株）
|
2016/03
|
2017/03
|
2018/03
|
2019/03
|
2020/03
|
2021/03
|
2022/03
|
2023/03
|
2024/03
|
2025/03
|
|
STATE STREET BANK AND TRUST COMPANY
|
|
|
|
|
1.66%
|
2%
|
-
|
-
|
-
|
1.97%
|
|
日本マスタートラスト信託銀行
|
|
|
|
|
5.27%
|
6.53%
|
12.64%
|
11.75%
|
10.06%
|
9.68%
|
|
塩野義製薬
|
|
|
|
|
4.96%
|
4.96%
|
4.96%
|
5.23%
|
5.57%
|
5.59%
|
|
3D WH OPPORTUNITY MASTER OFC － 3D WH OPPORTUNITY HOLDINGS
|
|
|
|
|
-
|
-
|
-
|
-
|
-
|
3.83%
|
|
日本カストディ銀行
|
|
|
|
|
-
|
5.11%
|
5.32%
|
5.51%
|
3.03%
|
2.39%
|
|
河野 博行
|
|
|
|
|
1.89%
|
1.89%
|
1.89%
|
1.99%
|
2.12%
|
2.13%
|
|
みずほ信託銀行株式会社
|
|
|
|
|
2.32%
|
1.6%
|
2.32%
|
2.44%
|
2.61%
|
2.12%
|
|
東邦ホールディングス従業員持株会
|
|
|
|
|
2.12%
|
2.27%
|
2.43%
|
2.55%
|
2.44%
|
2.09%
|
|
みずほ証券
|
|
|
|
|
-
|
-
|
-
|
-
|
2.43%
|
2.05%
|
|
BNY GCM CLIENT ACCOUNT JPRD AC ISG
|
|
|
|
|
-
|
-
|
-
|
-
|
3.03%
|
-
|
|
BNP PARIBAS FINANCIAL MARKETS
|
|
|
|
|
-
|
-
|
-
|
-
|
2.08%
|
-
|
|
JPモルガン証券
|
|
|
|
|
-
|
-
|
-
|
-
|
2.02%
|
-
|
|
GOLDMAN SACHS INTERNATIONAL
|
|
|
|
|
-
|
-
|
-
|
2.33%
|
-
|
-
|
|
SSBTC CLIENT OMNIBUS ACCOUNT
|
|
|
|
|
2.3%
|
-
|
2.1%
|
2.2%
|
-
|
-
|
|
MLI FOR CLIENT GENERAL OMNI NON COLLATERAL NON TREATY－PB
|
|
|
|
|
-
|
-
|
2.54%
|
1.88%
|
-
|
-
|
|
第一三共
|
|
|
|
|
-
|
-
|
-
|
1.63%
|
-
|
-
|
|
田辺三菱製薬
|
|
|
|
|
5.07%
|
5.07%
|
5.06%
|
-
|
-
|
-
|
|
NOMURA CUSTODY NOMINEES LIMITED OMNIBUS－FULLY PAID
|
|
|
|
|
-
|
-
|
1.94%
|
-
|
-
|
-
|
|
SSBTC CLIENT OMNIB US ACCOUNT
|
|
|
|
|
-
|
2.09%
|
-
|
-
|
-
|
-
|
|
日本トラスティ・サービス信託銀行
|
|
|
|
|
1.82%
|
-
|
-
|
-
|
-
|
-
|
|
J．P． MORGAN BANK LUXEMBOURG S．A．
|
|
|
|
|
-
|
-
|
-
|
-
|
-
|
-
|
|
河野博行
|
|
|
|
|
-
|
-
|
-
|
-
|
-
|
-
|
|
アステラス製薬
|
|
|
|
|
-
|
-
|
-
|
-
|
-
|
-
|
|
STATE STREET LONDON CARE OF STATE STREET BANK AND TRUST，BOSTON SSBTC A／C UK LONDON BRANCH CLIENTS－ UNITED KINGDOM
|
|
|
|
|
-
|
-
|
-
|
-
|
-
|
-
|
|
DEUTSCHE BANK AG LONDON－PB NON－TREATY CLIENTS 613
|
|
|
|
|
-
|
-
|
-
|
-
|
-
|
-
|
|
計
|
|
|
|
|
32.3%
|
33.83%
|
41.21%
|
37.51%
|
35.39%
|
47.25%
|